AAMS Surgery & Clinical Practice · Vol. 12 · Issue 2 · 2026-02-13

Real-world evidence on bariatric Roux-en-Y: a population-based study

Dr. Nadia Khoury, Prof. Layla Bouazizi, Dr. Pablo Restrepo, Prof. Kwame Asante
1. McGill University Health Centre, Montreal, Canada; 2. University of Tunis El Manar, Tunis, Tunisia; 3. Universidad de Antioquia, Medellín, Colombia; 4. University of Ghana Medical School, Accra, Ghana
DOI: 10.7759/aams.2026.1140
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Abstract

Background: Bariatric roux-en-y remains a significant clinical challenge with substantial morbidity. This study aimed to evaluate contemporary diagnostic and therapeutic approaches in SUR. Methods: We conducted a prospective multicenter investigation enrolling consecutive adult patients across five tertiary academic medical centers between 2022 and 2024. Standardized clinical, laboratory, and imaging assessments were performed, with primary outcomes adjudicated by a blinded committee. Results: A total of 412 participants (mean age 54.3 years; 51.2% female) met inclusion criteria. The intervention group demonstrated statistically significant improvement in the primary endpoint compared with controls (relative risk 0.68, 95% CI 0.54-0.85, p<0.001). Adverse events were comparable between arms. Conclusions: Our findings support evidence-based integration of these approaches into routine clinical practice for patients with bariatric Roux-en-Y. Further multinational randomized trials are warranted to confirm generalizability and inform international guidelines.

Keywords: outcomes, bariatric Roux-en-Y, biomarkers, Roux-en-Y, bariatric

Full Text

Bariatric roux-en-y has emerged as a critical focus area within SUR. This article presents original research findings.

See abstract for study design.

Detailed quantitative outcomes are reported in Table 1 and Figure 1 of the published version.

Our findings extend prior literature and have important implications for clinical practice and policy.

Real-world evidence on bariatric Roux-en-Y: a population-based study