AAMS Genetics & Molecular Medicine · Vol. 2 · Issue 2 · 2025-06-15
Liquid Biopsy ctDNA Analysis for Early Cancer Detection: Validation of a Multi-Cancer Panel
Anderson KL, Brown DM, Taylor RJ
Division of Oncologic Genetics, MD Anderson Cancer Center, Houston, TX, United States¹; Department of Pathology, Baylor College of Medicine, Houston, TX, United States²
Abstract
Validation study of a circulating tumor DNA panel for simultaneous detection of 15 cancer types in 8,500 asymptomatic individuals, achieving 93% specificity and 67% sensitivity for early-stage cancers.
Keywords: Liquid Biopsy, ctDNA, Cancer Screening, Multi-Cancer Detection, Early Diagnosis
Full Text
Validation study of a circulating tumor DNA panel for simultaneous detection of 15 cancer types in 8,500 asymptomatic individuals, achieving 93% specificity and 67% sensitivity for early-stage cancers.
This article is published open access by AAMS Genetics & Molecular Medicine. The complete peer-reviewed text can be read on the journal page.
Author Citation Metrics
- Anderson KL — Citations: 71 · h-index: 2 · i10-index: 2
- Brown DM — Citations: 521 · h-index: 13 · i10-index: 14
- Taylor RJ — Citations: 144 · h-index: 8 · i10-index: 8
Metrics are sourced from public bibliometric records (OpenAlex) and each author's Google Scholar profile.