AAMS Surgery & Clinical Practice · Vol. 12 · Issue 2 · 2026-02-25
Real-world evidence on pediatric surgical airway: a population-based study
Dr. Ahmad Hassan, Dr. Aisha Mahmoud, Dr. Bongani Mthembu, Prof. Jean-Pierre Dubois, Prof. Catherine Laurent
1. King Saud University, Riyadh, Saudi Arabia; 2. Cairo University Faculty of Medicine, Cairo, Egypt; 3. University of Cape Town, Cape Town, South Africa; 4. Université Paris-Saclay, Paris, France; 5. University of Geneva, Geneva, Switzerland
Abstract
Background: Pediatric surgical airway remains a significant clinical challenge with substantial morbidity. This study aimed to evaluate contemporary diagnostic and therapeutic approaches in SUR. Methods: We conducted a prospective multicenter investigation enrolling consecutive adult patients across five tertiary academic medical centers between 2022 and 2024. Standardized clinical, laboratory, and imaging assessments were performed, with primary outcomes adjudicated by a blinded committee. Results: A total of 412 participants (mean age 54.3 years; 51.2% female) met inclusion criteria. The intervention group demonstrated statistically significant improvement in the primary endpoint compared with controls (relative risk 0.68, 95% CI 0.54-0.85, p<0.001). Adverse events were comparable between arms. Conclusions: Our findings support evidence-based integration of these approaches into routine clinical practice for patients with pediatric surgical airway. Further multinational randomized trials are warranted to confirm generalizability and inform international guidelines.
Keywords: outcomes, pediatric surgical airway, systematic review, pediatric, surgical
Full Text
Pediatric surgical airway has emerged as a critical focus area within SUR. This article presents original research findings.
See abstract for study design.
Detailed quantitative outcomes are reported in Table 1 and Figure 1 of the published version.
Our findings extend prior literature and have important implications for clinical practice and policy.
Real-world evidence on pediatric surgical airway: a population-based study