AAMS Genetics & Molecular Medicine · Vol. 2 · Issue 1 · 2025-03-12
Mitochondrial DNA Variants and Their Association with Neurodegenerative Diseases: A Population-Based Study
Tanaka Y, Suzuki H, Nakamura T
Department of Molecular Genetics, University of Tokyo, Tokyo, Japan¹; National Center of Neurology and Psychiatry, Tokyo, Japan²
Abstract
Analysis of mitochondrial DNA variants in 28,000 Japanese individuals reveals significant associations between specific haplogroups and risk of Alzheimer disease and Parkinson disease.
Keywords: Mitochondrial DNA, Neurodegeneration, Population Genetics, Alzheimer Disease, Haplogroups
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