AAMS Genetics & Molecular Medicine · Vol. 1 · Issue 4 · 2024-12-05
Pharmacogenomic Predictors of Adverse Drug Reactions in Cardiovascular Therapy
Williams JA, Thompson SR
Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom¹; Oxford Centre for Personalized Medicine, Oxford, United Kingdom²
Abstract
This study evaluates pharmacogenomic variants in CYP2C19, CYP2D6, and VKORC1 as predictors of adverse drug reactions in 3,200 patients receiving cardiovascular medications, demonstrating significant clinical utility.
Keywords: Pharmacogenomics, Adverse Drug Reactions, Cardiovascular, CYP2C19, Personalized Medicine
Full Text
This study evaluates pharmacogenomic variants in CYP2C19, CYP2D6, and VKORC1 as predictors of adverse drug reactions in 3,200 patients receiving cardiovascular medications, demonstrating significant clinical utility.
This article is published open access by AAMS Genetics & Molecular Medicine. The complete peer-reviewed text can be read on the journal page.
Author Citation Metrics
- Williams JA — Citations: 186 · h-index: 1 · i10-index: 1
- Thompson SR — Citations: 0 · h-index: 0 · i10-index: 0
Metrics are sourced from public bibliometric records (OpenAlex) and each author's Google Scholar profile.