AAMS Internal Medicine & Therapeutics · Vol. 7 · Issue 3 · 2026-03-01

Proton Pump Inhibitor Deprescribing in Older Adults: A Cluster Randomized Trial

Byrne JP, Kim MS, Da Silva F
Beaumont Hospital, Dublin, Ireland; Ajou University Hospital, Suwon, South Korea; Hospital de Santa Maria, Lisbon, Portugal
DOI: 10.7759/aams.2026.1221
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Abstract

Cluster randomized trial evaluating a structured PPI deprescribing intervention in 62 primary care practices, enrolling 1,840 older adults on long-term PPI therapy.

Keywords: PPI deprescribing, older adults, polypharmacy, gastroesophageal reflux

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